eLife

Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide ...
Hosted on MSN

RNA strand that nearly self-replicates could unlock life’s origin

A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists closer than ever to demonstrating how life could have emerged from chemistry ...
The Conversation

RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Single-molecule RNA mapping may reveal how shape shifts steer health and disease

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method to study individual RNA molecules and reveal how their structures influence gene regulation, a ...

Bacterial defense system builds DNA in unexpected new way to stop viruses

Scientists at Stanford University have discovered that DRT3, a unique defense system found in bacteria, creates DNA to protect against viral infections. DRT3 is made up of two different enzymes called ...